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13-year-old female with only one small-sized right kidney
Presenting Chronic Kidney Disease (CKD)
Undergoing hemodialysis, three times per week, since March 2018
Dr. Michael M, East Africa
CKD on a unique atrophic right kidney with an unseen left kidney on ultrasound. Started hemodialysis in 2018 with Creatinine 655 mmol/L and Urea 37.9 mmol/L.
Clinical improvements in general body condition:
After the first dose of Chaperonze, her clinical results were good. Her Urea and Creatinine levels were stable and she was able to remain without hemodialysis for three months (versus three times per week for the past year).
BUN: 12 mmol/L
CREATININE: 368.9 mmol/L
UREA: ultrasound: right kidney measures 8.2 x 3.0 cm with decreased cortical medullary differentiation. Left kidney unseen.
BUN: 21 mmol/L
CREATININE: 450 mmol/L
UREA: ultrasound: bilateral echogenic small kidneys showing increased cortical reflectivity, cortical medullary distinction, right kidney measures 5.74 x 3.13 cm and left kidney measures 4.85 x 2.54 cm.
Clinical state remains stable in spite of NO dialysis treatment.
Blood results indicate kidney able to filter blood of Urea (BUN) and Creatinine without dialysis.
Ultrasonic evaluation indicates that the kidneys are stable and most probably an increase in functional tissue.